Ocimum basilicum extract Ameliorate Lead-induced Testicular Apoptosis in rats
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چکیده
The present study examined the efficacy of Ocimum basilicum extract, a natural herb, with antioxidant properties, against testicular toxicity induced by Lead, which is one of the most important toxic heavy metals. The intoxicated rats showed decreased cell proliferation was reflected by a decrease in Ki-67 expression, whereas the increase in apoptotic rate was associated with a decrease in the Bcl/Bax ratio. Concomitant treatment with aqueous basil extract led to an improvement in histological, morphometrical and immunohistochemical changes induced by lead. The beneficial effects of basil extract could be attributed to its antioxidant properties.
منابع مشابه
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